Our Science
At MESCH, we believe evolution is inevitable, but how we evolve is a choice. Through groundbreaking stem cell research and biotechnology, we guide human evolution toward a healthier, more abundant future. Our vision is not just about living longer but thriving with purpose, empathy, and wellness at the core of every innovation.
About our Chief Science Officer, Dr. Joshua Chou, PhD
Dr. Joshua Chou is a globally recognised scientist and innovator specialising in stem cell engineering and regenerative medicine. With a career dedicated to pushing the boundaries of biomedical science, his research focuses on harnessing the remarkable potential of stem cells to unlock new treatments for complex neurological conditions, including Parkinson’s disease and Alzheimer’s.
As a pioneer in his field, Dr. Chou has published extensively on groundbreaking approaches to cellular regeneration and tissue engineering. His work bridges the gap between theoretical research and real-world applications, with a mission to create therapies that improve the quality of life for millions of people globally.
Dr. Chou’s journey into stem cell science is deeply personal. Both he and MESCH co-founder Christopher Mesh have close family members battling Parkinson’s disease—a shared experience that ignited their determination to make a transformative impact on global health and wellbeing.
This personal connection inspires Dr. Chou’s relentless pursuit of innovative solutions. His commitment to translating cutting-edge research into practical, life-changing applications aligns seamlessly with MESCH’s mission to shape evolution for the better. By merging his scientific expertise with MESCH’s visionary goals, Dr. Chou is helping redefine what’s possible in the fields of longevity science and regenerative medicine.
Biotech and Beauty Converge
At the heart of MESCH’s innovation is our groundbreaking work in stem cell science. EXOGLO was born from this, and designed to unlock the natural regenerative powers of stem cells to awaken the skin’s true potential. Using cutting-edge biotechnology, we’ve created a formula that rejuvenates, regenerates, and renews skin like never before.
Stem Cell Technology
EXOGLO harnesses the power of Human Adipose Derived Mesenchymal Cell Exosomes and Human Stem Cell Conditioned Media — two key ingredients that activate cellular renewal and improve skin health at the deepest levels. These powerful components communicate with your skin’s natural systems, promoting healing and regeneration to deliver vibrant, healthy-looking skin.
Exosomes: Messengers of Possibility
Exosomes are nano-sized vesicles derived from human cells, including stem cells. These tiny messengers facilitate cellular communication, triggering important functions including healing and regeneration.
EXOGLO specifically utilises Human Adipose Derived Mesenchymal Stem Cell Exosomes (hAD-MSC Exosomes); cutting-edge, extracellular vesicles that play a crucial role in cell communication and skin regeneration.
These exosomes contain a concentrated blend of growth factors, proteins, and lipids that stimulate cellular repair, collagen production, and skin renewal. Clinical research shows that hAD-MSC Exosomes can significantly improve skin texture, smoothness, and overall skin structure by boosting collagen synthesis, accelerating cell turnover, and enhancing skin elasticity.
It's all about the Delivery
To ensure maximum efficacy, we’ve developed an advanced delivery system that utilises Phosphatidylcholine, Ceramides, and Phytosphingosine. This system enhances the penetration of our key actives while simultaneously strengthening the skin’s natural lipid barrier. The result? Deep, lasting hydration and an optimised environment for regeneration.
Ingredient Glossary
At EXOGLO, we believe in transparency and the power of science. Each ingredient in our formula has been carefully selected for its efficacy, working synergistically to deliver transformative results. Below is a detailed glossary of the ingredients in EXOGLO Serum, showcasing how each one contributes to skin regeneration, hydration, and vitality.
1,2-Hexanediol
A humectant and preservative that helps maintain moisture in the skin and stabilize formulations.
Ammonium Acryloyldimethyltaurate/VP Copolymer
A film-forming agent that gives the serum its smooth texture and helps it spread evenly on the skin.
Ascorbymethylcarbonyl Pentapeptide-72 Tri-t-Butyl Tryptophanamide
A peptide complex that supports skin renewal and promotes collagen production, improving firmness and reducing the appearance of wrinkles.
Ascorbyl Tetraisopalmitate
A stable, oil-soluble derivative of Vitamin C that brightens skin tone, reduces pigmentation, and boosts collagen production, contributing to a youthful appearance.
Butylene Glycol
A humectant that helps retain moisture in the skin, improving texture and hydration.
Caprylyl Glycol
A skin-conditioning agent with antimicrobial properties, helping to preserve the product and enhance its overall effectiveness.
Caprylic/Capric Triglyceride
A lightweight, non-greasy emollient that helps smooth the skin and improve its texture while providing hydration.
Carbomer
A gelling agent that creates a smooth texture and helps stabilize the serum.
Ceramide AP
A long-chain ceramide that supports the skin’s structural integrity. It helps lock in moisture over time, enhancing elasticity and firmness, making it particularly beneficial for addressing signs of aging, such as fine lines and sagging.
Ceramide NP
A non-polar lipid that closely mimics the skin’s natural ceramides. It replenishes lipids in the outer layer of the skin, restoring the barrier and preventing moisture loss. Ideal for sensitive or dry skin, it provides immediate hydration and protection from irritants.
Ceramide EOP
A ceramide essential for repairing the skin’s lipid matrix. It targets damage caused by environmental aggressors like UV rays and pollution, strengthening the skin’s defense mechanisms and promoting resilience against future stressors.
Cholestorol
A lipid that helps maintain the skin barrier, preventing moisture loss and keeping skin hydrated and protected.
Citrus Junos Peel Oil
An essential oil that provides antioxidant benefits, brightens the skin, and offers a refreshing scent.
Clitoria Ternatea Flower Extract
Rich in antioxidants, this extract helps protect the skin from oxidative stress and promotes a more even skin tone.
Curcuma Longa (Tumeric) Root Extract
Known for its anti-inflammatory and antioxidant properties, this extract helps calm the skin and reduce redness. DNA: A skin-conditioning agent that helps repair and protect the skin from damage, supporting regeneration and reducing signs of aging.
Defined Cell Culture Media 9
A nutrient-rich medium used to support the growth and maintenance of cells in the formulation, contributing to the efficacy of stem cell-based ingredients.
Dextrin
A skin-conditioning agent that helps improve moisture levels in the skin and enhance the absorption of other ingredients.
Dipotassium Glycyrrhizate
Derived from liquorice root, this ingredient has anti-inflammatory and soothing properties, helping to reduce redness and irritation.
DNA
A skin-conditioning agent that helps repair and protect the skin from damage, supporting regeneration and reducing signs of aging.
Docosahexaenoic Acid (DHA)
Another omega-3 fatty acid that helps maintain the skin’s lipid barrier and reduce inflammation.
Eicosapentaenoic Acid (EPA)
An omega-3 fatty acid that has anti-inflammatory properties, helping to soothe the skin and protect it from environmental damage.
Glycerin
A powerful humectant that draws moisture into the skin, helping to keep it hydrated and soft.
Human Adipose Derived Mesenchymal Cell Exosomes
These exosomes are rich in growth factors and signaling molecules, promoting cellular communication, regeneration, and renewal, helping the skin to repair and maintain health.
Human Stem Cell Conditioned Media
A potent ingredient that includes growth factors and cytokines to stimulate skin regeneration, repair damage, and enhance overall vitality for younger-looking skin.
Hydrogenated Lecithin
A phospholipid that improves skin hydration and helps stabilize emulsions, contributing to a smoother texture.
Pentylene Glycol
A moisturizing and antimicrobial agent that helps hydrate the skin while enhancing the effectiveness of other ingredients.
Phosphatidylcholine
A phospholipid that helps restore and strengthen the skin barrier, improve hydration, and enhance the penetration of other active ingredients.
Phytosphingosine
A lipid that naturally occurs in the skin, with anti-inflammatory and antimicrobial properties that support the skin barrier and calm irritated skin.
Pinus Pinaster Bark Extract
A potent antioxidant that helps protect the skin from free radical damage, reducing signs of aging and supporting skin elasticity.
Polyglutamic Acid
A powerful hydrating agent that can hold more moisture than hyaluronic acid, helping to maintain skin hydration and elasticity.
Polysorbate 80
An emulsifier that helps blend oil and water-based ingredients, ensuring a smooth, consistent texture.
Potassium Hyrdoxide
A pH adjuster that helps balance the acidity of the formula, ensuring it is gentle and effective on the skin.
PPG-4-Ceteth-20
A surfactant that helps improve the spreadability of the serum and ensures even application.
Propanediol
A natural solvent and humectant that enhances the penetration of active ingredients and helps retain moisture in the skin.
Sodium Lauroyl Lactylate
A skin-conditioning agent that helps improve moisture retention and enhances the absorption of other active ingredients.
t-Butyl Alcohol
A solvent used to help dissolve other ingredients and enhance the texture of the serum.
Sorbitol
A humectant that helps attract and retain moisture in the skin, providing hydration.
Squalane
A lightweight, non-comedogenic emollient that mimics the skin’s natural oils, providing hydration and improving skin elasticity.
Tocopheryl Acetate
A form of Vitamin E that provides antioxidant protection, helps moisturize the skin, and improves skin texture.
Tremella Fuciformis Polysaccharide
Derived from snow mushrooms, this ingredient acts as a natural moisturizer, holding water in the skin, and has antioxidant properties.
Xanthan Gum
A thickening agent that provides stability to the formulation and helps the serum spread evenly on the skin.
Water
A solvent used as a base for many skincare formulations, helping to dissolve other ingredients.